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It is often called the "master antioxidant" because it is found in high concentrations in almost every cell in the human body

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Reagents, including the inhibitors and mouse lines, can be requested from the corresponding author and will be distributed upon reasonable request and availability to fill all requests

Examples of peptide tags include AviTag, a peptide allowing biotinylation by the enzyme BirA and so the protein can be isolated by streptavidin (GLNDIFEAQKIEWHE) Calmodulin-tag, a peptide bound by the protein calmodulin (KRRWKKNFIAVSAANRFKKISSSGAL) FLAG-tag, a peptide recognized by an antibody (DYKDDDDK) HA-tag, a peptide recognized by an antibody (YPYDVPDYA) His-tag, 5-10 histidines bound by a nickel or cobalt chelate (HHHHHH) Myc-tag, a short peptide recognized by an antibody (EQKLISEEDL) S-tag (KETAAAKFERQHMDS) SBP-tag, a peptide which binds to streptavidin (MDEKTTGWRGGHVVEGLAGELEQLRARLEHHPQGQREP) Softag 1, for mammalian expression (SLAELLNAGLGGS) Softag 3, for prokaryotic expression (TQDPSRVG) V5 tag, a peptide recognized by an antibody (GKPIPNPLLGLDST) Xpress tag (DLYDDDDK) Examples of protein tags include BCCP (Biotin Carboxyl Carrier Protein), a protein domain recognized by streptavidin Glutathione-S-transferase-tag, a protein which binds to immobilized glutathione Green fluorescent protein-tag, a protein which is spontaneously fluorescent and can be bound by nanobodies Maltose binding protein-tag, a protein which binds to amylose agarose Nus-tag Strep-tag, a peptide which binds to streptavidin or the modified streptavidin called streptactin (Strep-tag II: WSHPQFEK) Thioredoxin-tag