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Lipid-related metabolism: AML cells are dependent on OXPHOS [118,119,120], AML cells obtain free fatty acids from bone marrow adipocytes and utilize fatty acid oxidation (FAO) and OXPHOS to maintain AML cell survival and growth [121,122,123]

While the current evidence base is promising, it is important to approach DSIP with realistic expectations

doi: 10.3390/molecules25163731 118 ChuXLiWHinesMGLyakhovIMellorsJWDimitrovDS

Peptides can make sense if you are: Already doing the basics reasonably well but stuck Dealing with metabolic strain, weight gain, prediabetes, or cardiometabolic risk Struggling with recovery, inflammation, or injury that is not resolving with standard care Working on sleep and stress but still not getting traction after proper evaluation Looking for structured, measurable, medically supervised support, not experimentation They are usually not a good idea if you are: Pregnant or trying to conceive without a clear plan and specialist guidance Managing active cancer or high risk cancer situations without oncology input Looking for a quick cosmetic shortcut with no lifestyle foundation Not willing to do follow up, labs, or basic behavior changes Using peptides sourced outside medical care What a good peptide plan looks like in real life This part matters because peptide therapy should feel boring in the best way