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Oftentimes, too-high levels of oxidative stress and Glutathione depletion can lead to multiple diseases, including neurodegenerative disorders (Alzheimers, Parkinsons), pulmonary disease (asthma, COPD), immune disease (HIV, autoimmune disease), cardiovascular diseases (hypertensions), liver disease, cystic fibrosis, and aging

That lower pH is necessary for certain research compounds that simply won't dissolve at neutral pH

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This isn't a pharmacological side effect of AHK-Cu so much as a handling consideration, but it belongs in an honest safety picture because community AHK-Cu use is almost entirely self-prepared