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Oral: variable absorption

69 - 73 Likewise, it occurs after vascular occlusion, 94 neuromuscular blockade (succinylcholine application), 45 potassium or magnesium overload, 43 , 111 dopamine system failure (nigrostriatal damage [1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, MPTP]), 130 vesicle depletion (reserpine), 132 dopamine receptors blockade (haloperidol and other dopamine antagonists), 47 , 116 , 135 or dopamine receptors supersensitivity (amphetamine after haloperidol) 133 or dopamine over-release (amphetamine)

However, response may vary: Higher baseline weight Individuals starting at higher body weights may experience: Slower percentage weight loss initially Need for full maintenance doses to achieve optimal effects Potentially better tolerance of higher doses Lower baseline weight Those with lower starting weights might: Achieve therapeutic goals at submaximal doses (e.g., 2.4 mg vs

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