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constructed a hyaluronic acid (HA)-modified zeolitic imidazolate framework for loading DOX and QUE, prioritizing targeting HEPPG2/DOX resistant cells overexpressed CD44

N-formylkynurenine is then hydrolyzed into kynurenine by arylformamidase (AFMID) 32

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Stereotactic administration of 25-OHC into the corpus callosum facilitated the recruitment of IBA1 + microglial, which was accompanied by the activation of caspase-1 in an NLRP3-dependent manner, leading to the increased IL-1 production