chac1 glutathione degradation of enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases
Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione degrading enzyme CHAC1 ScienceDirect Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease
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