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10.3390/nu12051351 57 CiuleanuT.BazinI.LungulescuD.MironL.BondarenkoI.DeptalaA.et al (2016)

Steric and conformational features of the aconitase mechanism

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Multidrug resistance transporters also contribute to DOX deprivation in cancers including bladder cancer, esophageal squamous cell carcinoma, or breast cancer, by overexpression of MRP2 (cMOAT or ABCC2) and are mainly responsible for its efflux [378,379,380]