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Upon reception of a signal to migrate such as chemical mediators called chemokines present near the edge of the wound the bound pool of actin monomers becomes immediately available to form actin filaments in the lamellipodium and filopodia of migrating cells

Gowen et al., 2020)

Circulating endothelial cells (CEC) and progenitors (CEP) and VEGFR-1-expressing monocytes as biomarkers for patients (pts) with renal cell carcinoma (RCC)