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MAPK pathways, including ERK, p38, and JNK are generally pro-survival, and increased activation of these pathways is generally correlated with increased platinum resistance [35]

The smaller peaks for (S-S) and (C-S) were still visible, however a clear trend could not be seen due to the overlap with phosphate bands: E.g ., the (S-N = O) mode could hardly be observed in the difference spectra

However, I looked again and they also had a little picture diagram above the directions of one capsule and one glass of water. Thanks to the addition of the diagram to assist users in understanding the directions, our tester gave a 5 out of 5 score in this area