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Chronic pain can make it difficult to perform daily activities such as working, sleeping or enjoying other leisure activities

An IV drip can rehydrate you, replenish nutrients and deliver medications without relying on the digestive system

Additional information Peer review information Nature Communications thanks Caryn Outten, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Choline can be supplied from diet, or made in the body as phosphatidyl choline via the PEMT enzyme There can be SNPS in PEMT, reducing activity, or it may be depleted by reduced methylation as it is SAMe-dependent