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6.1.4 Microsponges Microsponge-based carriers have been investigated as a potential platform for transdermal flavonoid delivery, providing a porous structure conducive to prolonged release and enhanced skin deposition ( in vitro release of 92.3% within 24 h

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It has been observed that the apoptotic process in paclitaxel induced-painful neuropathy is due to the permeability transition pore opening, with the consequent cytochrome c release and Ca 2+ homeostasis dysregulation (Areti et al., 2014)