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The cytotoxic K + in endolymph could reach the tympanic scala through the orifice of the cupula cochleae and then reach the lymphatic space of the Cortis organ, where the contact of K + with hair cells leads to the destruction of cochlear sensory epithelial cells, atrophy of stria vascularis and degeneration of auditory nerve fibers

That's the double-edged sword in a sentence: the same property that makes IGF-1 LR3 powerful for stimulating muscle growth also removes the natural brakes that normally keep IGF-1 signaling safe

However, LeGSTU2 expression was repressed by low temperature

Accessed 25 Mar 2023 World Health Organization (2022) Cardiovascular diseases