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Consistent with these predictions, the most significant differences in gene expression were seen for genes (e.g., N-cadherin (CDH2), versican (VCAN), L6 cell surface antigen (TM4SF1) and layilin (LAYN)) associated with cell invasion, migration, metastasis and the epithelialmesenchymal transition

295 , L648L657 (2008)

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Soluble IL-6R and IL-6 complex facilitate IL-6 signal transduction in diverse cells (e.g., nerve cells, smooth muscle cells, and endothelial cells) where GP130 alone is present on the surface [8-10]