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Conclusions: Metabolic biomarkers reflecting INS resistance and lipotoxicity are associated with early cardiac remodeling in obesity

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- Gallbladder disease: Gallstones or other conditions may also lead to high blood lipase levels because it results in obstruction affecting the pancreas

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Mitochondrial damage caused by oxidative stress can trigger the release of metals in mitochondrial proteins (Mittler et al., 2004)

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