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This is especially true for the heart, where a great deal of its energy is derived from fatty acids

Environmental Exposures and Lung Aging: Molecular Mechanisms and Implications for Improving Respiratory Health

Yokoyama K, Kawanishi M, Sugie A, et al

Targeting other metabolic enzymes, including hexokinase 2 and PDH kinase 1, using agents such as 2-deoxy-D-glucose and dichloroacetate (DCA), has demonstrated potential in reducing lactate production and suppressing tumor growth (175,176)