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The adaptive immune system and a strong TH1 response increasing production of IFN- is needed to combat intracellular pathogens and Babesia , while a strong Th2 response with an increase in IL-4 production and B cell production of antibodies is essential for host defense against extracellular pathogens and Lyme disease [132]

Nat Protoc 628:120124 Muthusamy S, Lundin D, Mamede Branca RM, Baltar F, Gonzlez JM, Lehti J, Pinhassi J (2017) Comparative proteomics reveals signature metabolisms of exponentially growing and stationary phase marine bacteria

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