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In the second model, the cells were subject to a heat shock treatment at 45 C in an incubator for 15 mins

Hyperglycemia induces endoplasmic reticulum stress in atrial cardiomyocytes, and mitofusin-2 downregulation prevents mitochondrial dysfunction and subsequent cell death

In this context, analyses using epigenetic risk scores indicate that DNA methylation patterns associated with chronic inflammation are associated with both the prevalence and incidence of depression ( Alterations in the GR gene and in the epigenetically sensitive regulators of GR play a significant role

2 Organ-on-chip in the 3D in vitro models framework OoCs allow researchers to model human diseases in the lab using immortalized or donor-derived cells cultured in organ-specific microenvironments