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Controlled human data is more limited, which is why it remains a research-use compound in most jurisdictions the gap between animal and human evidence is its most-cited limitation

Barrett's esophagus is a condition in which an abnormal columnar epithelium replaces the stratified squamous epithelium that normally lines the distal esophagus

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However, we previously reported intracellular levels of these mediators in relation to GPX4 activity (7) that are likely similarly altered here