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Doses of 200-500 mcg are common

Millions of treatments have been carried out worldwide and when Vitamin B12 has been sourced from a reputable pharmacy and administered by a medically qualified healthcare practitioner, the risks are very low

Mecobalamin should be used with caution in individuals with a history of heart disease, particularly if they are at risk for arrhythmias, as large doses may cause changes in heart rhythm

Biomolecules 11:1515 Boohaker RJ, Lee MW, Vishnubhotla P, Perez JLM, Khaled AR (2012) The use of therapeutic peptides to target and to kill cancer cells