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(2) NMN co-treatment was conducted by adding 90 L of 250/500 M NMN for four hours prior to chemotherapy treatment, and this was performed by adding 20 L from a series of descending drug concentrations to the cell culture plate with either bleomycin, cisplatin, doxorubicin, etoposide, gemcitabine, methotrexate, paclitaxel or vincristine

So, CBS is not only a homocysteine producing enzyme but in many cell models it also can explain increased redox pressure, lipid peroxidation and cellular stress resistance

Environ Sci Technol 51:43684376

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