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Nevertheless, until long-term human data accumulates, the precautionary approach remains appropriate

This gene-regulatory capacity appears to be central to its observed effects, effectively recalibrating cellular activity towards a state of regeneration and homeostasis

Effects can depend on dose, product type, and whether THC is present

Multiple clinical trials and controlled studies have demonstrated: Statistically significant improvements in skin firmness and elasticity with consistent use Reduction in fine lines and wrinkle depth over 3-6 months of application Improved skin density, moisture retention, and surface texture Reduction in photodamage and hyperpigmentation Tightening of loose skin documented in both topical and injectable applications Citation: Leyden JJ et al