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MiR-206, being one of the most well-studied miRNAs in AD, has been described to be implicated in the pathogenesis of AD due to suppression of BDNF expression in the brain

doi: 10.1073/pnas.91.21.10114

& Schrider, D

After its initial release for Windows systems, several Half-Life ports were developed for additional platforms, including the Playstation 2, Macintosh and Dreamcast