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Description

Simple Combinations of Lineage-Determining Transcription Factors Prime Cis-Regulatory Elements Required for Macrophage and B Cell Identities

In vivo L2-Cmu validation studies were performed in 45-mo-old C57BL/6J male mice (Jackson Labs, Bar Harbor, ME)

To validate our findings, we used atp-3 RNAi, a positive control, which is known to cause mitochondrial fragmentation due to ATP synthase dysfunction 85,86