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Description

Upon activation, CD8 T cells rapidly accumulate 2HG that promotes H3K27me3 and enhances H3K4me3 at promoter regions, with only minor effects on DNA demethylation

The experiment was performed with three independent replicates

sedebokerense , possibly controlling the initiation and termination of the pathogenicity through epigenetic modifications and benefiting the pathogen by allowing it to adapt to changing environments upon infection