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10.1016/j.ijrobp.2013.08.051 Int

For instance, the observed downregulation of ADRB2 could potentially influence lipolysis via the G inhibitory protein (Gi)-cAMP-Phosphodiesterase 4 (PDE4) axis 63 , and modulate BCL3 trafficking through Beta-Arrestin 2 (-arrestin2)/Extracellular Signal-regulated Kinase (ERK) signaling 64