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AFB1 also displayed a similar binding affinity to interact with bovine serum albumin (BSA) binding site I with a binding constant of nearly 4.20 10 4 M 1 (193)

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3.2.1 TGVS theory According to the TGVS theory, which combines blood vessels, nerves, and neurotransmitters, the trigeminal nerve and peri-vascular nerve fibers both inside and outside the skull serve as the main pathways for transmitting pain in migraines