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In isolated mice intestinal tissue, DMB also reduced the intestine smooth muscle spontaneous contraction and inhibited KCl, acetylcholine, BaCl 2 , or histamine-induced intestine smooth muscle active tension, while the active frequency was unaffected

doi: 10.1016/j.jconrel.2014.08.016

Ipamorelin itself doesnt usually cause true weight gain, but some people experience temporary water retention or increased appetite that can make the scale fluctuate

reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)