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In the case of hysterectomy, pretreatment with GnRHA reduced duration of surgery (9.59 minutes, 95% CI 15.9 to 3.28) and of blood loss (MD 25 mL to 148 mL), led to a lower utilization of blood transfusions (OR 0.54, 95% CI 0.3 to 1.0), and fewer postoperative complications (OR 0.54, 95% CI 0.3 to 0.9)

investigated IGF-1 expression in a canine flexor tendon repair model at 10 days post-operation using immunohistochemical staining, revealing a significant increase in IGF-1 levels ( Although the timing of IGF-1 upregulation varies across studies, likely due to differences in species, experimental methods, and tendon locations, the consensus is that IGF-1 expression is significantly elevated during tendon healing

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Dis Markers (2004) 20(45):20713