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During the last several years, there have been significant discoveries regarding the role of BAs in immunity and inflammation

3336 Mitochondrial dysfunction manifests in multiple aspects, including mutations and deletions in mitochondrial DNA (mtDNA), disrupted calcium homeostasis, depolarization of the mitochondrial membrane, abnormal fusion and fission processes, impaired mitochondrial biogenesis, and oxidative stress

Deprescribing inappropriate or unnecessary medications impacts clinical outcomessuch as reduction in hospitalizations, ED visits, falls and overall healthcare costsmitigates ADEs, and improves quality of life

Several studies have explored the therapeutic application of both native and mimetic forms of SOD to counteract this oxidative burden (Table 1)