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doi: 10.1016/j.micpath.2020.104709 6 ZhouCBZhouYLFangJY

2024 May:292:110046

Shaikh AS, Thomas AB, Chitlange SS

OTHER REGULATORS OF THE PENTOSE PHOSPHATE PATHWAY It has been shown that the activation of mammalian target of rapamycin complex 1 (mTORC1) increases the metabolic flux through both glycolysis and the oxidative arm of the pentose phosphate pathway ( In contrast, the non-oxidative arm of the pentose phosphate pathway is enhanced in the presence of oncogenic Kras (Kras G12D ) in pancreatic tumors (Ying et al., 2012)