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Piccoli L, Park Y-J, Tortorici MA, Czudnochowski N, Walls AC, Beltramello M, et al

Neurological Applications Both peptides have demonstrated some therapeutic potential in neurological applications, though this represents a less extensively studied area

A nonsteroidal cream called a topical calcineurin inhibitor (TCI) that controls your body's immune response can also help prevent itching

The pathogenetic mechanisms underlying this syndrome include disruption of hunger/satiety centers (damage to arcuate, ventromedial, and paraventricular hypothalamic nuclei), leptin resistance despite elevated circulating leptin levels, autonomic dysregulation with reduced energy expenditure, hypothalamic-pituitary axis dysfunction, and local inflammatory processes [87, 88]