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U24AG047867) and the UK ESRC and BBSRC (award no

One study noted that GsDEVs suppressed LPS-induced NLRP3 inflammasome activation in macrophages, suggesting potential to reduce inflammasome-driven lung injury (relevant in severe pneumonia and sepsis) [220]

This is accomplished through tightly regulated uptake and efflux and through the expression of metal-binding proteins, such as metallothioneins, that effectively sequester pools of zinc and copper