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Expert Opin Biol Ther 2008;8:195562

Despite extensive research, technical development and clinical experimentation, no current surgery-based, material-based, cell-based or drug-based treatment can reliably restore the structure and function of hyaline cartilage

In addition, ROS signaling regulating the transcription of IL-4 [179] IL-6, IL-8 [180] and TNF- [181, 182] is regulated by a thiol-dependent mechanism

ECG were recorded after mild sedation with ketamine (50 mg/kg body weight) and xylazine (5 mg/kg body weight), using a 60 W light bulb to maintain warmth, using a lead II system with three electrodes configuration: the negative electrode was placed on the right forelimb, the positive electrode on the left hind limb, and the neutral electrode on the right hind limb