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Urol ., 181 (2), 741751

Lu CS, et al

We generated a combinatorial library by mutating complementarity-determining region (CDR) positions 29 - 32 of CDR-L1, 50 of CDR-L2, and 94 - 96 of CDR-L3, introducing at each explored position amino acid diversity informed by deep mutational scanning previously performed for R023 (Fig