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These numbers reflect more than correlation

In animal models of heart failure, BPC-157 showed some cardioprotective signals, but these were recorded in specific injury contexts, not in healthy cardiovascular systems exposed to supraphysiologic peptide concentrations

PMCID: PMC5295439

Because previous studies have demonstrated that NAD + depletion can induce cellular senescence, while the senescence associate secretory phenotype (SASP) in turn can induce CD38 26,27 , it was important to examine the impact of Ab68 on p21, a widely used albeit non-specific marker of cellular senescence