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The data is improving, the regulatory environment is more favorable, and the safety profile remains strong

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Specifically, a review of clinical trials on the use of BPC-157 has characterized it as safe both in treating inflammatory bowel disease and wound healing, noting that no events of toxicity had been reported throughout those trials [12]

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It has previously been established that the presence of an additional amino acid between the 0 and +1 position is tolerated and our data confirm that there are only small changes in binding energy between RVxF and RxVxF peptide variants (Fig 5D and E)

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