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Description

19,20,21 The TME constitutes a multifaceted and dynamic ecosystem comprising an assortment of cell types, including tumor cells, immune cells, and stromal cells, in addition to components of the extracellular matrix

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The activation of glutamate receptors can enhance the effectiveness of the effectors T cells, or decrease the cytokine production in immunosuppressive myeloid-derived suppressor cells, increasing the antitumor immune response

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Retrieved February 16, 2022, from American Heart Association | To be a relentless force for a world of longer, healthier lives

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Saddoughi S, Mitchell KG, Fruth K, Allen MS, Nichols FC, Harmsen S, Cassivi S, Wigle D, Taswell J, Mounajjed T, Walsh GL, Hofstetter WL, Swisher SG, Roth JA, Sepesi B, Vaporciyan AA, Rice DC, Antonoff MB , Blackmon SH

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