glutathione antioxidant ncbi system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Glutathione Participation in the Prevention

Another mechanism involves activating death receptors of TNFR superfamily expressed on target cells, which binds procaspase-8 after activation of their ligands on NK cells, allowing its activation and triggering apoptotic pathways

"In Utero and Intra-Partum HIV-1 Transmission and Acute HIV-1 Infection during Pregnancy: Using the BED Capture Enzyme-Immunoassay as a Surrogate Marker for Acute Infection." Int J Epidemiol 40.4 (2011): 945-54

The Phase 2 trial published in the New England Journal of Medicine studied doses ranging from 1mg to 12mg weekly

Doeppner TR, Kaltwasser B, Elali A, Zechariah A, Hermann DM, Bhr M