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D-Nle-Tyr-Ile-NH-(CH 2 ) 5 - CONH 2 appeared to be extensively distributed outside the central blood compartment and/or bound within the tissues as evidenced by its large volume of distribution (Vd)

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In contrast, approximately 92% and 87% of D-CuP remained unchanged after 0.5 and 4 h of protease K exposure, highlighting its superior protease stability

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