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In preclinical models , it has been shown to influence reproductive hormone regulation and cellular activity in gonadal tissues

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Pharmacokinetics, pharmacodynamics and formulation strategies for enhanced bioavailability of baicalein: an update

Alcohol induces CYP2E1, the enzyme responsible for converting Ace 125 mg to its toxic metabolite NAPQI, and simultaneously depletes hepatic glutathione reducing the liver's capacity to detoxify NAPQI