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[7] In type 2 RCD, healthy lymphocytes are replaced by abnormal lymphocytes, increasing the risk of complications such as enteropathy-associated T-cell lymphoma (EATL), severe malabsorption, and ulcerative jejunoileitis, and results in poorer outcomes

When Not to Use Eflornithine Known hypersensitivity to eflornithine or cream excipients Broken, inflamed, or infected skin in the application area Children ( 6 months: Continue maintenance if satisfied

MTHFR protein exists as a homodimer comprising two N-terminal catalytic domains with binding sites for NADPH, methylene-THF, and cofactor FAD-linked to the regulatory domain (C-terminus) (Figure 2B)

This circulation maintains bile acid pool stability while controlling bile acid synthesis rates through feedback regulation