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NAFLD is a broad spectrum of diseases that encompasses simple fatty liver and nonalcoholic hepatitis (NASH), which can progress to cirrhosis and liver cancer

10.1016/j.freeradbiomed.2017.01.027 74

A growing body of research suggests low-dose colchicine (generally 0.5 mg per day) may reduce the risk of blood clot-related cardiovascular events such as heart attack and strokeespecially when used in conjunction with other standard cardiovascular medicationsthrough its ability to reduce inflammatory signaling in blood vessels

However, CTX is associated with significant reproductive toxicity, which adversely affects the reproductive health of patients undergoing chemotherapy for breast cancer 10,11,12