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Description

Each sample was half-diluted with cold serine and poured into a Lymphoprep tube (Axis-Shield, Oslo, Norway)

doi:10.1155/2019/4874921

In BRAF V600E-mutant CRC, tumor cells often exhibit an initial response to BRAF inhibitors, but frequently develop resistance through reactivation of the MAPK pathway, commonly via KRAS amplification or MEK mutations [76]