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and 5) revealing how the mitochondria adapts to ultimately shift its physiology from steady-state

Besides, berberine down-regulates the expression of acetylcholinesterase and inhibits acetylcholinesterase activity in Alzheimers disease model mice hippocampus which induced by heavy metals, in addition, berberine normalizes the production of inflammatory factors, such as tumor necrosis factor-alpha (TNF-), IL-6, IL-1 (Hussien et al., 2018)

In preliminary studies, GGsTop was assessed for its ability to inhibit GGT enzyme activity in vivo in mouse lung and serum at 0.5 mg/kg and 5 mg/kg

As described, the cGAS-STING pathway is a canonical in innate inflammatory stress responses, not only within neurons and glial cells of the CNS but also across a broad range of peripheral tissues, contributing to diverse pathological contexts such as cancer (Chakraborty et al., 2024