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A saline-locked angiocatheter was inserted into the participants arm, allowing for the collection of 5 mL of blood at each designated time point

The authors stated that the statistically significant effects were weak and could partly reflect an incidental deterioration within the placebo group

But it stressed that dose-response relationships were not established and that there is insufficient clinical safety information to characterize BPC-157's human safety profile with no studies administering it to humans by the proposed routes

It is also important to note that clomiphene may increase the likelihood of twin pregnancy