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doi: 10.1002/mco2.49 7 MorrisseySMYanJ

doi:10.1371/journal.pgen.1000155

Future studies are needed to reconcile the underlying differences between tumor tissue and basal PTC cell line GPX4 expression levels and in vitro responses to pharmacologic inhibition of GPX4 within an emulated 3D thyroid tumor microenvironment in vitro and in vivo

Overall the above reported evidence on the involvement of GSH and the redox environment are only some issues that deserve to be further investigated to comprehend the several aspects characterizing the possible crosstalk between redox reactions and modulation of ATG