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Our laboratory systematically characterized the cell signaling mechanisms underlying Mn-induced oxidative stress

The increase in antioxidant defense was supported by the reduced ROS levels observed in 1919 GBM PSPH amp and 1919 GBM PSPH V116I cells compared to parental cells (Fig

This diverse regulatory network allows CHAC1 to play a crucial role in maintaining cellular homeostasis and adapting to environmental stresses

Currently, the two conflicting methods of supplying D-lactate (DL) and depleting lactate manipulate macrophages toward the M1 phenotype for tumor immunotherapy