low glutathione chronic fatigue Symptoms of and How to Fix It The Role of Glutathione Metabolism

BMC Bioinformatics 6 , 31 (2005)

Cch dng: Ung 1 vin/ln, chia lm 2 ln/ngy

This metabolic program (Figure 1) includes increased nutrient uptake (mainly glucose often in combination with Gln) and increased flux of glucose through the glycolytic pathway and PPP, thereby generating essential building blocks for amino acid and nucleotide biosynthesis as well as NADPH necessary for driving reductive biosynthetic pathways (especially for nucleotides and FAs/lipids) and maintaining the redox homeostasis

Other metabolic pathways regulated by shear stress In addition to glycolysis, FA metabolism, and mitochondrial respiration, shear stress regulates other metabolic pathways in ECs with relevance to aging and vascular dysfunction