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The patient complained of severe, sharp, stabbing pains on the right side of his face involving the mandibular, maxillary and ophthalmic branches of the trigeminal nerve

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Other FDA-approved drugs, including donepezil, galantamine, rivastigmine, and memantine, have demonstrated cognitive benefits but are frequently associated with gastrointestinal disturbances, dizziness, agitation, and, in some cases, severe hepatotoxicity, as observed with tacrine (Marucci et al., 2021

A direct analgesic action has been recognized, suggesting that BTX-A mechanism providing pain relief may act through an alternative mode of action