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The kidney and brain also accumulates Cbl

10.19845/j.cnki.zfysjjbzz.2013.04.007 59 LiuY.GaoJ

The lone pair (LP(1)) on the oxygen atom of GHB (O 71 ) donates into the * anti-bonding orbital of the C 69 -O 70 bond within GHB itself, with a high second-order perturbation energy (E 2 ) of 30.77 kcal.mol 1

The turnover of ECM proteins is enzymatically regulated by ECM proteases, degrading enzymes belonging to the metzincin family, including matrix metalloproteinases (MMPs), $\alpha$-disintegrin and metalloproteinases (ADAMs) and $\alpha$-disintegrin and metalloproteinases with thrombospondin motifs (ADAMTSs) [23]